Lewinsohn, DM;
Leonard, MK;
LoBue, PA;
Cohn, DL;
Daley, CL;
Desmond, E;
Keane, J;
Lewinsohn, DA;
Loeffler, AM;
Mazurek, GH;
O'Brien, RJ;
Pai, M;
Richeldi, L;
Salfinger, M;
Shinnick, TM;
Sterling, TR;
Warshauer, DM;
Woods, GL.
BACKGROUND: Individuals infected with Mycobacterium tuberculosis (Mtb) may develop symptoms and signs of disease (tuberculosis disease) or may have no clinical evidence of disease (latent tuberculosis infection [LTBI]). Tuberculosis disease is a leading cause of infectious disease morbidity and mortality...
Nahid, P;
Dorman, SE;
Alipanah, N;
Barry, PM;
Brozek, JL;
Cattamanchi, A;
Chaisson, LH;
Chaisson, RE;
Daley, CL;
Grzemska, M;
Higashi, JM;
Ho, CS;
Ho, CS;
Hopewell, PC;
Keshavjee, SA;
Lienhardt, C;
Menzies, R;
Merrifield, C;
Narita, M;
O'Brien, R;
Peloquin, CA;
Raftery, A;
Saukkonen, J;
Schaaf, HS;
Sotgiu, G;
Starke, JR;
Migliori, GB;
Vernon, A.
The American Thoracic Society, Centers for Disease Control and Prevention, and Infectious Diseases Society of America jointly sponsored the development of this guideline for the treatment of drug-susceptible tuberculosis, which is also endorsed by the European Respiratory Society and the US National Tube...
Ren, CL;
Esther CR, Jr;
Debley, JS;
Sockrider, M;
Yilmaz, O;
Amin, N;
Bazzy-Asaad, A;
Davis, SD;
Durand, M;
Ewig, JM;
Yuksel, H;
Lombardi, E;
Noah, TL;
Radford, P;
Ranganathan, S;
Teper, A;
Weinberger, M;
Brozek, J;
Wilson, KC.
"BACKGROUND:
Infantile wheezing is a common problem, but there are no guidelines for the evaluation of infants with recurrent or persistent wheezing that is not relieved or prevented by standard therapies.
METHODS:
An American Thoracic Society-sanctioned guideline development committee selected clinical...
Early detection of tuberculosis (TB) is essential to improve health outcomes for people with TB, and to reduce TB transmission more effectively. Systematic screening in high risk groups is a complement to efforts to improve the patient-initiated pathway to TB diagnosis (that is, diagnosing TB among peopl...
Early detection of tuberculosis (TB) is essential to improve health outcomes for people with TB, and to reduce TB transmission more effectively. Systematic screening in high risk groups is a complement to efforts to improve the patient-initiated pathway to TB diagnosis (that is, diagnosing TB among peopl...
This Guideline outlines the purpose and the target audience of the second edition of Guidance for national tuberculosis programmes on the management of tuberculosis in children. It discusses the difference between TB in children and adolescents and TB in adults and provides an estimate of the burden of c...
WHO has developed guidelines on systematic screening for active tuberculosis (TB) based on a thorough review of available evidence. Early detection of TB is essential to further improve health outcomes for people with TB, and to reduce TB transmission more effectively. Systematic screening in high risk g...
Research over the past decade has resulted in the development of two commercial interferongamma release assays (IGRAs), based on the principle that the T-cells of individuals who have acquired TB infection respond to re-stimulation with Mycobacterium tuberculosis-specific antigens by secreting interferon...
Earlier and improved tuberculosis (TB) case detection - including smear-negative disease, often associated with HIV co-infection - as well as expanded capacity to diagnose multidrug-resistant tuberculosis (MDR-TB) are global priorities for TB control. Conventional laboratory methods are slow and cumberso...